Status:
COMPLETED
DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Localized Osteosarcoma
Metastatic Osteosarcoma
Eligibility:
All Genders
Brief Summary
This research study is studying DNA biomarkers in tissue samples from patients with osteosarcoma. Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctor...
Detailed Description
OBJECTIVES: I. To comprehensively detect genomic, epigenomic, and transcriptomic aberrations in tissue samples from patients with osteosarcoma that may play a role in chemoresistance and metastasis u...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Diagnosis of osteosarcoma
- Fresh-frozen samples collected at the time of diagnosis with matchedblood DNA (preferred) from patients enrolled on the following osteosarcoma biology protocols:
- COG-P9851
- COG-AOST06B1
- Available clinical outcome data
- Not specified
- Not specified
Exclusion
Key Trial Info
Start Date :
August 6 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT01190943
Start Date
August 6 2010
Last Update
March 28 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Childrens Oncology Group
Philadelphia, Pennsylvania, United States, 19104