Status:

COMPLETED

fMRI Cholinergic Mechanisms in Schizophrenia

Lead Sponsor:

US Department of Veterans Affairs

Conditions:

Schizophrenia

Eligibility:

All Genders

18-60 years

Brief Summary

This study aims to determine how clozapine treatment improves neuronal measures of sensory gating in subjects with schizophrenia.

Detailed Description

This study will use functional magnetic resonance imaging (fMRI) to study patients treated with risperidone, a commonly used neuroleptic that does not improves sensory gating, to those treated with cl...

Eligibility Criteria

Inclusion

  • Diagnosis of schizophrenia
  • age 18-60 yrs

Exclusion

  • claustrophobia
  • weight \> 250 lbs
  • metal in body other than dental fillings

Key Trial Info

Start Date :

October 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2011

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01191827

Start Date

October 1 2008

End Date

December 1 2011

Last Update

May 15 2015

Active Locations (1)

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VA Eastern Colorado Health Care System, Denver

Denver, Colorado, United States, 80220