Status:
COMPLETED
Effects of HIgh Volume COntinuous REnal Replacement Therapy in Patients With Septic Acute Kidney Injury
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
Gambro Renal Products, Inc.
Conditions:
Sepsis
Kidney Failure, Acute
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
Acute kidney injury (AKI) is a common and serious problem in critically ill patients, and is known to be an independent risk factor for mortality. Among the various etiologies of AKI, sepsis or septic...
Eligibility Criteria
Inclusion
- Consensus criteria for sepsis
- Injury stage of RIFLE criteria or more (\>2-fold increase in the serum creatinine or urine output \<0.5 mL/kg/hr for 12 hours)
- Absence of other established non-sepsis-related cause of AKI
- written informed consent
Exclusion
- patient age \< 20 years or \> 80 years
- life expectancy less than 3 months (ex. terminal stage of malignancy)
- Child-Pugh class C liver cirrhosis
- Pregnancy or lactation
- History of dialysis prior to the randomization
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2015
Estimated Enrollment :
212 Patients enrolled
Trial Details
Trial ID
NCT01191905
Start Date
January 1 2011
End Date
July 1 2015
Last Update
August 19 2015
Active Locations (5)
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1
National Health Insurance Corporation Ilsan Hospital
Koyang, South Korea, 410-719
2
Seoul National University Bundang Hospital
Seongnam, South Korea, 463-707
3
Seoul National University Hospital
Seoul, South Korea, 110-752
4
Severance Hospital
Seoul, South Korea, 120-752