Status:
COMPLETED
Soluble Triggering Receptor Expressed on Myeloid Cells in Severe Acute Pancreatitis
Lead Sponsor:
Changhai Hospital
Conditions:
Acute
Pancreatitis
Eligibility:
All Genders
18-90 years
Brief Summary
Early diagnosis of secondary infection of necrotic tissue in severe acute pancreatitis is extremely important. The investigators evaluated whether the level of soluble TREM-1 (sTREM-1) in fine needle ...
Detailed Description
The major cause of death, next to early organ failure, is secondary infection of pancreatic or peripancreatic necrotic tissue, leading to sepsis and multiple organ failure. The diagnosis and treatment...
Eligibility Criteria
Inclusion
- 18 years of age or older
- Diagnosis of severe pancreatitis
- Pancreatic or peripancreatic necrosis
- Body temperature at least 38.3°C
- Leukocytosis (more than 10,000 leukocytes per cubic millimeter) or leukopenia (fewer than 4000 leukocytes per cubic millimeter)
Exclusion
- A flare-up of chronic pancreatitis
- End-stage chronic diseases (including pancreatic and bile duct cancer)
- Previous drainage or surgery for confirmed or suspected infected necrosis
- An acute intraabdominal event (e.g., perforation of a visceral organ, bleeding, or the abdominal compartment syndrome)
Key Trial Info
Start Date :
July 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01193413
Start Date
July 1 2008
End Date
November 1 2009
Last Update
September 2 2010
Active Locations (1)
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1
Changhai Hospital, Second Military Medical University
Shanghai, China, 200433