Status:
UNKNOWN
A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease
Lead Sponsor:
Baylor Research Institute
Conditions:
Aortic Valve Disease
Eligibility:
All Genders
18+ years
Brief Summary
For this study, blood and tissue samples will be collected in order to perform genetic testing to help researchers gather information about this disease and how and why it affects some patients more t...
Detailed Description
The cause of bicuspid aortic valve (BAV) and its associated co morbidities is unknown. There is, however, evidence supporting a genetic cause for the BAV, Pedigree analysis of familial clustering init...
Eligibility Criteria
Inclusion
- Patients \> or = to 18 years of age
- Presenting with aortic stenosis and to undergo elective aortic valve replacement or repair with or without aortic aneurysm dilation repair
- Able to sign informed consent document
Exclusion
- Patients unable to provide informed consent for any reason
- Patients with predominant aortic regurgitation valve disease
- Patients with other known connective tissue disorders (such as Marfan's Syndrome, Ehlers-Danlos Syndrome)
Key Trial Info
Start Date :
September 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT01194362
Start Date
September 1 2010
End Date
December 1 2022
Last Update
March 8 2022
Active Locations (1)
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1
The Heart Hospital Baylor Plano
Plano, Texas, United States, 75093