Status:
COMPLETED
Early Primary Prophylaxis of Esophageal Varices
Lead Sponsor:
Institute of Liver and Biliary Sciences, India
Conditions:
Cirrhosis
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Patients of cirrhosis with portal hypertension aged 18 to 75 years who have small esophageal varices with or without red color signs and have not bled previously will be enrolled. After baseline evalu...
Eligibility Criteria
Inclusion
- \- Patients of cirrhosis with portal hypertension aged 18 to 75 years who have small esophageal varices with or without red color signs and have not bled previously.
Exclusion
- Any contra-indication to beta-blockers
- Any EVL or sclerotherapy within last 3 months
- Child Turcotte Pugh (CTP) score \> 12, refractory ascites, hepatorenal syndrome
- Any past history of surgery for portal hypertension
- Significant cardio or pulmonary co-morbidity
- Any malignancy that affects survival.
- Active alcohol abuse or last intake ≤ 4 weeks to avoid possibility of ongoing alcohol hepatitis.
- Past history of surgery for portal hypertension
- Uncontrolled diabetes
- Peripheral vascular disease
- Refusal to participate in the study
Key Trial Info
Start Date :
November 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT01196507
Start Date
November 1 2010
End Date
April 1 2014
Last Update
June 15 2016
Active Locations (1)
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1
Institute of Liver & Biliary Sciences (ILBS)
New Delhi, National Capital Territory of Delhi, India, 110 070