Status:
COMPLETED
Role of Fibrocytes in Chronic Obstructive Pulmonary Disease
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
40+ years
Brief Summary
Chronic obstructive pulmonary disease (COPD) is a frequent airway disease characterized by both bronchial inflammation and remodelling. Bronchial mucosa is infiltrated by macrophages, neutrophils and...
Eligibility Criteria
Inclusion
- Patients: diagnostic of Chronic obstructive pulmonary disease (COPD) exacerbation.
- Control group: subjects without any history of lung disease and with normal lung function testing. Subjects will be separated in 2 sub-groups according to smoking history (Never smokers, smokers (former or current) and paired to patients according to age and sex.
- Written informed consent
Exclusion
- Subject without any social security or health insurance
- Asthma, lung fibrosis or idiopathic pulmonary hypertension
- Chronic viral infections (hepatitis, HIV)
Key Trial Info
Start Date :
March 11 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2016
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT01196832
Start Date
March 11 2011
End Date
May 31 2016
Last Update
February 9 2022
Active Locations (1)
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1
CHU de Bordeaux
Pessac, France, 33604