Status:

COMPLETED

Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy

Lead Sponsor:

The Cleveland Clinic

Collaborating Sponsors:

Health Resources and Services Administration (HRSA)

Conditions:

Liver Transplantation

Kidney Transplantation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

We hypothesize that delayed graft function and ITBS events may be related to small blood clots (microthrombi) that collect in the kidneys and liver after cardiac death. Treatment of the DCD organs wit...

Detailed Description

The waiting list for kidney and liver transplantation continues to increase in the United States, and therefore the need grows for additional donor organs. Utilization of organs donated after cardiac ...

Eligibility Criteria

Inclusion

  • Adults aged 18 years and older
  • Subjects willing/able to provide written consent
  • Subjects willing/able to comply with study requirements
  • Subjects who will receive a solitary organ transplant

Exclusion

  • Subjects requiring multi-organ transplants
  • Women who are pregnant
  • Subjects with current severe systemic infection
  • Subjects with an active infection

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2018

Estimated Enrollment :

103 Patients enrolled

Trial Details

Trial ID

NCT01197573

Start Date

April 1 2010

End Date

May 1 2018

Last Update

August 28 2018

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University Hospitals / Case medical Center

Cleveland, Ohio, United States, 44106

2

Cleveland Clinic

Cleveland, Ohio, United States, 44195