Status:

COMPLETED

Racial and Genetic Biomarkers of Response in Tissue Samples From Patients With Endometrial Cancer

Lead Sponsor:

Gynecologic Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Stage I Uterine Corpus Cancer

Stage II Uterine Corpus Cancer

Eligibility:

FEMALE

Brief Summary

This research study is studying racial and genetic biomarkers of response in tissue samples from patients with endometrial cancer. Studying samples of tissue from patients with cancer in the laborator...

Detailed Description

PRIMARY OBJECTIVES: I. To identify racial categorization as the proportion of genetic background of African-American or European-American women with endometrioid endometrial cancer (EEC). II. To eva...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Histologically confirmed endometrial cancer
  • Stage I-IV disease regardless of grade
  • Underwent surgical staging including hysterectomy, bilateral oophorectomy, washings, and pelvic lymphadenectomy
  • Eligible and evaluated on GOG-0210 clinical trial, a Molecular Staging Study in Endometrial Cancer
  • Available frozen or formalin-fixed and paraffin-embedded normal tissue that is free of tumor cells and yields sufficient high-quality normal DNA for testing
  • Consented their specimens and clinical data to be collected and used in future studies
  • Self-declared African-American or Caucasian race

Exclusion

    Key Trial Info

    Start Date :

    January 1 2010

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 1 2017

    Estimated Enrollment :

    243 Patients enrolled

    Trial Details

    Trial ID

    NCT01198171

    Start Date

    January 1 2010

    End Date

    February 1 2017

    Last Update

    August 14 2024

    Active Locations (1)

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    Gynecologic Oncology Group

    Philadelphia, Pennsylvania, United States, 19103

    Racial and Genetic Biomarkers of Response in Tissue Samples From Patients With Endometrial Cancer | DecenTrialz