Status:

UNKNOWN

Tumorspecific T-cell Immunity in Bladder Cancer as Prognostic Marker

Lead Sponsor:

Technical University of Munich

Conditions:

Bladder Cancer

Eligibility:

All Genders

18-90 years

Brief Summary

Bladder cancer is generally susceptible to immunotherapeutic measures. The investigators will characterize 40 patients with muscle-invasive bladder cancer regarding the existence and frequency of tumo...

Eligibility Criteria

Inclusion

  • Histologically confirmed muscle-invasive urothelial carcinoma
  • Age \> 18 years
  • Hemoglobin \> 10g/dl
  • Signed Informed Consent
  • Karnofsky index \< 70%

Exclusion

  • Clinically relevant second malignancy
  • Severe comorbidities (e.g. NYHA III, end-stage renal disease)
  • Chronic infectious disease (HIV, Tuberculosis)
  • Immunosupression
  • Severe psychiatric diseases
  • Blood donation in the last 4 weeks

Key Trial Info

Start Date :

August 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT01198808

Start Date

August 1 2010

Last Update

January 18 2012

Active Locations (1)

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1

Urologische Klinik der Technischen Universität München

Munich, Bavaria, Germany, 81675