Status:

COMPLETED

Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5

Lead Sponsor:

Odense University Hospital

Conditions:

Osteopetrosis

Eligibility:

All Genders

8+ years

Brief Summary

The aim of the study is to describe patients with a high bone mass phenotype due to a mutation in the low density lipoprotein l receptor 5 gene (LRP5) and compare them with age and sex matched control...

Detailed Description

Cases and controls are closely matched on age and sex and evaluated cross-sectionally. Dual x-ray absorptiometry (DXA) and high resolution peripheral quantitative computed tomography (HR-pQCT) are us...

Eligibility Criteria

Inclusion

  • Lrp5 mutation/ADOI

Exclusion

  • Pregnancy

Key Trial Info

Start Date :

January 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT01199094

Start Date

January 1 2009

End Date

June 1 2010

Last Update

September 10 2010

Active Locations (1)

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Odense University Hospital, Osteoporosis Clinic

Odense, Denmark, 5000