Status:
COMPLETED
The Effect of an Opioid on the Lower Esophageal Sphincter During Anesthesia Induction
Lead Sponsor:
Region Örebro County
Conditions:
Lower Esophageal Sphincter
Eligibility:
All Genders
18-40 years
Phase:
PHASE4
Brief Summary
This study evaluates the effects of adding an opioid (alfentanil) during anesthesia induction with respect to the barrierpressure in the esophagogastric junction. The secondary aim was to investigate...
Detailed Description
During anesthesia induction and tracheal intubation one major concern is to avoid passive regurgitation of gastric content and aspiration. The lower esophageal sphincter is a muscle located at the di...
Eligibility Criteria
Inclusion
- Healthy volunteer 18-40 years old
- Informed,signed and dated consent
Exclusion
- Pharyngoesophageal dysfunction
- Gastro/intestinal-,cardiovascular-,lung- or neurologic disease
- Ongoing medication
- Allergy to alfentanil, propofol, soya or peanuts
- Pregnancy or breast-feeding
- BMI\>30
- Participation in other clinical trial -ongoing or during last 30 days.
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT01199458
Start Date
September 1 2010
End Date
October 1 2010
Last Update
November 9 2016
Active Locations (1)
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1
Örebro University
Örebro, Sweden, 21740