Status:
COMPLETED
POCD in Elderly Patients Following Desflurane or Sevoflurane General Anesthesia
Lead Sponsor:
Loma Linda University
Conditions:
1. Postoperative Cognitive Dysfunction
Eligibility:
All Genders
65+ years
Brief Summary
The use of desflurane in elderly subjects (\>65 years old) undergoing general anesthesia with endotracheal intubation will result in decreased POCD compared to sevoflurane if the patient's MAP is with...
Eligibility Criteria
Inclusion
- Adult patients (\>65 years old)
- Scheduled for elective surgery requiring general anesthesia at LLUMC HSH
- Airway management expected to include endotracheal intubation
- Expected surgical duration 120 to 240 minutes
Exclusion
- Pre-existing significant psychiatric disease or mental status changes
- Clinically significant cardiovascular, respiratory, hepatic, renal,neurological, psychiatric, or metabolic disease
- Patient's weighing \>50% ideal body weight
- Men: Ideal Body Weight (in kilograms) = 50 + 2.3 kg per inch over 5 feet
- Women: Ideal Body Weight (in kilograms) = 45.5 + 2.3kg per inch over 5 feet
- Patients who have undergone a general anesthetic within the past 7 days
- Patient refusal
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT01199913
Start Date
August 1 2010
End Date
August 1 2014
Last Update
September 9 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Loma Linda University
Loma Linda, California, United States, 92354