Status:

COMPLETED

HYPONCO - Hypoxia in Brain Tumors

Lead Sponsor:

University Hospital, Caen

Conditions:

Anaplastic Glioma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Background : In malignant gliomas, hypoxia is associated with tumour angiogenesis and tumour progression. This multidisciplinary preclinical and clinical project aims to validate the use of 18F-FMISO...

Eligibility Criteria

Inclusion

  • adults aged \>= 18 years
  • KPS \>= 70%
  • must have the understanding and ability to sign an informed consent document
  • be male or non-pregnant
  • non-lactating females
  • Patients who are fertile must agree to use an effective method of contraception during participation in the study
  • the following laboratory results : absolute neutrophil count \>= 1500 cells/µl, platelet count \>= 100,000 cells/µl, SGOT \<= 2.5 x ULN, serum creatinine \<= 1.5 x ULN

Exclusion

  • contraindication to surgery
  • concomitant radio-, chemo-, or immunotherapy
  • known diagnosis of Human Immunodeficiency Virus (HIV) infection
  • patient with hepatitis B or C
  • diabetic patient
  • patient with kidney or liver deficiency

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2012

Estimated Enrollment :

39 Patients enrolled

Trial Details

Trial ID

NCT01200134

Start Date

October 1 2010

End Date

July 1 2012

Last Update

November 19 2012

Active Locations (1)

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1

Caen University Hospital

Caen, France, 14033