Status:
COMPLETED
Impact of the PET in the Diagnosis Strategy of FUO or Inflammatory Syndrome in Immunocompetent Patients FUO-TEP
Lead Sponsor:
University Hospital, Limoges
Conditions:
Fever
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fever of unknown origin (FUO) and chronic inflammatory syndrome could be seen in many affections. The diagnostic process is still a challenge and could not be specified yet after several clinical stud...
Detailed Description
All patients with FUO and chronic inflammatory syndrome will undergo FDG-PET/CT and conventional morphologic imaging modalities. Results of these two diagnostic procedures in identifying diagnostic cl...
Eligibility Criteria
Inclusion
- Patient with FUO criteria:
- Fever since 3 weeks, Temperature \> 38.3°C, No diagnostic after 3 days of hospitalization.
- Patient with periodic fever criteria:
- Fever with criteria like FUO, Fever-free intervals, and apparent remission of the underlying disease, At least 3 febrile episodes.
- Inflammatory syndrome without any clinical sign, Important inflammatory syndrome: Erythrocyte sedimentation rate ≥ 50 at the first hour, and elevation of at least one another inflammatory parameter (haptoglobin, orosomucoïd, fibrinogen or C-reactive protein), Evolution since more than 3 weeks, No diagnostic orientation after clinical examination and history-taking, No diagnostic clue after 3 days of hospitalisation.
- Oral informed consent obtained.
Exclusion
- Demented patient or unable to receive information on the protocol and to give informed consent.
- Pregnant women, or without contraception.
- Contraindication to iodine examination, gallium scintigraphy or 18FDG TEP-scan.
- Immunodeficient patient.
- Know HIV infection, neutropenic patient and nosocomial fever.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT01200771
Start Date
May 1 2008
End Date
February 1 2014
Last Update
July 20 2025
Active Locations (19)
Enter a location and click search to find clinical trials sorted by distance.
1
Médecine Interne - CHU
Amiens, France, France, 80080
2
Médecine Nucléaire - CHU
Amiens, France, France, 80080
3
Médecine Interne - CHU
Lille, France, France, 59037
4
Médecine Nucléaire et Imagerie Fonctionnelle - CHU
Lille, France, France, 59037