Status:
COMPLETED
Two-site Intradermal Influenza Vaccination in Elderly
Lead Sponsor:
Queen Saovabha Memorial Institute
Conditions:
Influenza
Eligibility:
All Genders
60-100 years
Phase:
NA
Brief Summary
One-site dose sparing intradermal influenza vaccination in elderly had been studied but resulted in unsatisfactory outcomes. The investigators evaluate the safety and immunogenicity of the two-site in...
Detailed Description
The subjects would be randomly divided into three groups of 60 subjects each. Group1 receives a single intramuscular dose of 0.5 ml of trivalent influenza vaccine, containing at least 15 microgram of ...
Eligibility Criteria
Inclusion
- healthy male or female volunteer aged at least 60 years old
- willing to participate in this study
Exclusion
- previous influenza vaccination within 6 months
- systemic ypersensitivity to egg or chicken proteins or any of the vaccine components
- history of a life-threatening reaction to the study vaccine or a vaccine containing the same constituents.
- ongoing acute febrile illness (oral temperature, ≥37.5 c )
- congenital or acquired immunodeficiency
- treatment with immunosuppressive or other immune- modifying drugs or cancer therapy within previous 6 months
- long-term treatment with systemic corticosteroids
- receipt of blood or blood-derived products in the previous 3 months
- history of thrombocytopenia or a bleeding disorder contraindicating for intramuscular vaccination.
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2018
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT01202552
Start Date
October 1 2010
End Date
April 1 2018
Last Update
April 6 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Queen Saovabha Memorial Institute
Bangkok, Thailand, 10330