Status:
COMPLETED
Effect of Statin Treatment on Insulin Sensitivity During Myocardial Infarction
Lead Sponsor:
Brasilia Heart Study Group
Conditions:
Myocardial Infarction
Eligibility:
All Genders
40-65 years
Phase:
PHASE4
Brief Summary
Stress hyperglycemia during myocardial infarction (MI) is related to mortality at short and long term. Recent studies, however, revealed that chronic statin treatment may decrease both insulin sensiti...
Detailed Description
Stress hyperglycemia during myocardial infarction (MI) is a predictor of worse prognosis at short and long term. From the mechanistic standpoint, hyperglycemia can attenuate thrombolysis, increase pla...
Eligibility Criteria
Inclusion
- Less than 24 hours after the onset of MI symptoms
- ST-segment elevation of a least 1 mm (frontal plane) or 2 mm (horizontal plane) in two contiguous leads
- Myocardial necrosis, as evidenced by increased Creatine Kinase-MB (CK-MB) and troponin levels
Exclusion
- Diabetes or prior use of statins in the last 6 months
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT01205347
Start Date
October 1 2010
End Date
September 1 2013
Last Update
September 10 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital de Base do Distrito Federal
Brasília, Federal District, Brazil, 70000.000