Status:

RECRUITING

Mediators of Atherosclerosis in South Asians Living in America

Lead Sponsor:

University of California, San Francisco

Collaborating Sponsors:

Northwestern University

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Atherosclerosis

Cardiovascular Diseases

Eligibility:

All Genders

40-84 years

Brief Summary

South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though Sout...

Eligibility Criteria

Inclusion

  • South Asian ancestry defined by having at least 3 grandparents born in one of the following countries: India, Pakistan, Bangladesh, Nepal, or Sri Lanka
  • age between 40 and 84 years.

Exclusion

  • Physician diagnosed heart attack, stroke or transient ischemic attack (TIA), heart failure, or angina (or use of nitroglycerin)
  • Current atrial fibrillation
  • Past history of cardiovascular procedures (coronary artery bypass graft (CABG) Surgery, angioplasty, valve replacement, pacemaker or defibrillator implantation, or any surgery on the heart or arteries)
  • Active treatment for cancer
  • Life expectancy less than 5 years due to serious medical illness
  • Impaired cognitive ability as judged by the reviewer
  • Plans to move out of the study region in next 5 years
  • Weight greater than 300 pounds
  • Living in a nursing home or on a waiting list
  • Unable to speak/read/write English, Hindi, Urdu, or Bangla

Key Trial Info

Start Date :

September 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

2314 Patients enrolled

Trial Details

Trial ID

NCT01207167

Start Date

September 1 2010

End Date

December 1 2025

Last Update

March 25 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University of California, San Francisco

San Francisco, California, United States, 94115

2

Northwestern University

Chicago, Illinois, United States, 60611

3

New York University

New York, New York, United States