Status:
COMPLETED
Articular Cartilage Resurfacing With Mesenchymal Stem Cells In Osteoarthritis Of Knee Joint
Lead Sponsor:
Royan Institute
Conditions:
Osteoarthritis
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
Knee osteoarthritis is the most common form of arthritis. Treatments involve high costs in terms of social and economic, are palliative and do not contemplate healing by regenerative therapy. It has b...
Detailed Description
Mesenchymal stem cells are pluripotent cells that can be obtained from various tissues .They have shown capabilities to differentiate into bone,cartilage,muscle,and adipose tissue, representing a new ...
Eligibility Criteria
Inclusion
- Female patients not pregnant or lactating.
- Patients with a history of corticosteroids or on active therapy, will only be eligible for enrollment if corticosteroid use is suspended for 1 month prior cell therapy
- Marcaine 0.75% و Lidocaine 4% test performed to be assure the exact location of the pain is related to the knee.
- Diagnosis must be based on magnetic resonance imaging.
- Both genders
- Age:18-65 years
Exclusion
- Diagnosis of cancer,DM,CNS disorder,thyroid disease or respiratory disease.
- Known allergic reaction to components of study treatment and/or study injection procedure
- Patients infected with hepatitis B,C or HIV.
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT01207661
Start Date
August 1 2009
End Date
November 1 2010
Last Update
January 5 2012
Active Locations (1)
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1
Royan Institute
Tehran, Iran