Status:
COMPLETED
Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
Heidelberg University
Conditions:
Paraplegia, Spinal
Myelomeningocele
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to use functional MRI (fMRI) and magnetic resonance (MR) diffusion tensor imaging (DTI) to investigate brain activation and white matter changes in patients with congenita...
Detailed Description
Recently new approaches to spinal cord repair have been successfully established in animal models. Promising therapies for promoting spinal axonal regeneration in man will be available in the near fut...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Paraplegic patients (Th1-Th12, ASIA A),
- Myelomeningocele patients (Th1-Th12 ASIA A)
- Acute SCI 2-6 months, chronic SCI 12-24 months
- Exclusion criteria:
- Traumatic brain injury (TBI)
- Neurological diseases other than spinal cord lesion
- MRI incompatibility
- Pressure sores
- methicillin-resistant Staphylococcus aureus (MRSA)
Exclusion
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2013
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT01208584
Start Date
August 1 2008
End Date
October 1 2013
Last Update
March 11 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital, Basle (only study site!)
Basel, Switzerland