Status:

COMPLETED

Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction

Lead Sponsor:

University of Aarhus

Conditions:

Healthy

Eligibility:

MALE

18-70 years

Phase:

NA

Brief Summary

This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by that is stimulating lipolysis on expense of IGF-I production. This is done in 10 healthy men on calorie restr...

Detailed Description

It has been shown that calorie restriction enhances the length of life in yeast, worms, fish and rodent. Whether this elongation of life due to calorie restriction can be applied to humans is not know...

Eligibility Criteria

Inclusion

  • healthy lean men
  • age \>18

Exclusion

  • metabolic disturbances
  • alcohol drug abuse
  • malign disease: current or previous

Key Trial Info

Start Date :

September 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2011

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01209429

Start Date

September 1 2010

End Date

September 1 2011

Last Update

September 13 2011

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Hospital of Aarhus, Norrebrogade

Aarhus, Denmark, 8000