Status:
COMPLETED
Systemic Zinc Sulphate in Treatment of Recurrent Aphthous Ulcerations:A Doubleblind, Placebo Controled Study
Lead Sponsor:
Qazvin University Of Medical Sciences
Conditions:
Aphthous Stomatitis
Eligibility:
All Genders
10+ years
Phase:
PHASE2
Brief Summary
Recurrent aphthous stomatitis (RAS) is one of the most common of oral mucosa diseases that affects approximately 20% of the general population. Despite the fact that clinical, pathologic and therapeut...
Detailed Description
Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of man characterized by painful ulceration recurring with varying frequency. The pathophysiology of aphthous ulcers remains partly...
Eligibility Criteria
Inclusion
- A history of Recurrent aphthous stomatitis
- Patients who had symptoms such as burning sensation, pain
- Patients not on any immunosuppressive or immunomodulatory treatment .
- Patients of both sexes over 10 years with recurrent aphthous stomatitis
- Patients who gave written informed consent
- Patients who were willing for evaluation after therapy and every 1 month up to 5months
Exclusion
- Participants demonstrating drug consumption in the 7 past months
- pregnancy or lactation
- Any kind of localized or systemic disease, especially ulcerative colitis , chorn disease and Bechet's syndrome
- Smokers
- patients receiving immunosuppressive treatments or any kind of systemic or local drugs especially systemic antibiotics (in past 2 weeks ) and oral antihistamines( in past month ) were either eliminated or asked to discontinue their treatment for a minimum of one month before entering the investigation.
Key Trial Info
Start Date :
April 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01210014
Start Date
April 1 2008
End Date
August 1 2009
Last Update
September 28 2010
Active Locations (1)
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1
Qazvin university of medical sciences
Qazvin, Qazvin Province, Iran, 3415759811