Status:
COMPLETED
Vitamin D in Bronchiolitis Obliterans Syndrome
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Collaborating Sponsors:
KU Leuven
Conditions:
Allograft Rejection
Lung Transplantation
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Vitamin D deficiency occurs in around 50% of our transplant population. Preventive treatment with Vitamin D (D-cure) can reduce the prevalence of Bronchiolitis Obliterans Syndrome after lung transplan...
Detailed Description
* Prospective, interventional, randomized, double-blind, placebo-controlled trial. * Clinical setting (tertiary University Hospital). * Investigator-driven, no pharmaceutical sponsor. * Lung transplan...
Eligibility Criteria
Inclusion
- Stable LTx recipients at discharge after transplantation.
- Signed informed consent
- Adult (age at least 18 years old at moment of transplantation)
- Able to take oral medication
Exclusion
- Prolonged and/or complicated Intensive care unit-course after transplantation.
- Early (\<30 days post-transplant) post-operative death
- Major suture problems (airway stenosis or stent)
- Retransplantation (lung)
- Previous transplantation (solid organ)
- Multi-organ transplantation (lung+ other solid organ)
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01212406
Start Date
October 1 2010
End Date
August 1 2015
Last Update
November 11 2015
Active Locations (1)
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1
UZ Gasthuisberg
Leuven, Belgium, 3000