Status:
TERMINATED
Immunophenotyping of Peripheral T Cells After T Cell Depletion With Alemtuzumab
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
American Society of Transplant Surgeons
Conditions:
Kidney Transplant
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to check the T and B cells of the immune system in 50 newly transplanted patients whom have received a kidney (50 recipients and 50 donors totaling 100 anticipated partici...
Detailed Description
The purpose of this study is to check the T and B cells of the immune system in 50 newly transplanted patients whom have received a kidney (50 recipients and 50 donors totaling 100 anticipated partici...
Eligibility Criteria
Inclusion
- Adult subjects between ages 18-65 years old of either gender
- Recipients have an available ABO compatible living donor for transplant
- Subjects are listed to be a single-organ transplant recipient (kidney only)
- Subjects have the ability to provide informed consent
Exclusion
- Subjects have panel reactive antibody greater than 35%
- Subjects have the potential to have a high recurrence rate of their primary renal disease (i.e. Focal Segmental Glomerulonephritis )
- Subjects who have a history of Hepatitis C
- Subjects who have had a previous organ transplant
- Subjects are unable to fully understand the purpose of the study, thereby unable to give a fully informed consent
- Subjects with a positive lymphocytotoxic crossmatch using donor lymphocytes and recipient serum
- Subjects who are pregnant or nursing
- Subjects who, due to the existence of a surgical, medical or psychiatric condition, other than the current transplant, which in the opinion of the investigator, precludes enrollment into this trial.
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2009
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT01213329
Start Date
February 1 2006
End Date
April 1 2009
Last Update
April 10 2019
Active Locations (1)
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1
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611