Status:
COMPLETED
Effects Of Chlorhexidine Mouthrinse On Peridontopathogens: A Randomized, Placebo-Controlled Study
Lead Sponsor:
Ege University
Conditions:
This Study Evaluated the Effectiveness of Chlorhexidine Mouthrinse on Subgingival Microbiota
Eligibility:
All Genders
18-45 years
Phase:
PHASE4
Brief Summary
The aim of this study is to evaluate the therapeutic effectiveness of chlorhexidine mouthrinse on gingival inflammation and subgingival microbiota in addition to daily mechanical plaque control in a p...
Detailed Description
Failure to perform oral hygiene adequately at the gingival margin results in the formation of a pathogenic plaque that has the potential to initiate gingivitis and in some individuals to progress to p...
Eligibility Criteria
Inclusion
- 18-45 years old male or female with gingivitis associated with dental plaque, no clinical signs of destructive periodontal disease, clinical attachment loss \< 3mm, a minimum of 20 teeth (teeth that have gross caries, were fully crowned or extensively restored, orthodontic banded, abutments, or third molars were not included in the tooth count).
Exclusion
- use of tobacco products, history or current manifestation of systemic disease which could impair immune response such as diabetes mellitus, immunological disorders, hepatitis and HIV infections, use of antibiotic or anti-inflammatory or immunosuppressive drugs during 3 months period prior to the start of the trial, periodontal therapy during the last 3 month, pregnancy or lactation and oral contraceptives usage.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01213550
Start Date
March 1 2006
End Date
December 1 2007
Last Update
October 4 2010
Active Locations (2)
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1
Ege U School of Dentistry
Izmir, Bornova, Turkey (Türkiye), 35100
2
Ege University School of Dentistry Dep of Periodontology
Izmir, Bornova, Turkey (Türkiye), 35100