Status:

COMPLETED

Cancer Survival Through Weight Loss and Exercise

Lead Sponsor:

Pennington Biomedical Research Center

Conditions:

Breast Cancer Survivors

Eligibility:

FEMALE

30-75 years

Phase:

NA

Brief Summary

To test the effectiveness and feasibility of intensive motivational, behavior modifying intervention aimed at improving physical activity and dietary habits to produce at least 7% weight loss in women...

Detailed Description

This study will be divided into two phases (Phase I and II) that will differ by the intensity of motivational intervention. In Phase I, participants will receive 6 months of intensive weekly group-bas...

Eligibility Criteria

Inclusion

  • Women between the ages of 30 and 75.
  • Positive history of breast cancer treatment completed at least 2 months but no longer than 36 months prior to randomization.
  • BMI ≥ 25 kg/m2 and ≤ 45 kg/m2
  • Not involved in regular physical activity or weight loss management programs.
  • Stage I, II or IIIa breast cancer with good prognosis.

Exclusion

  • Presence of any co-morbidities including cardiovascular disease or diabetes
  • Fasting triglycerides \> 500 mg/dl.
  • Consume more than 14 alcoholic beverages per week.
  • A history of drug abuse, or excess alcohol consumption (40g/day)6.
  • Currently dieting or engaging in any activity with the goal of losing weight.
  • Significant intentional weight loss in the past year (\> 50 lbs in the past year) or current use of weight loss medications.
  • History of gastrointestinal bypass or other bariatric surgery in the last 3 years.
  • Pregnant or plan on becoming pregnant in the next 12 months.
  • Factors that may limit adherence to intervention or affect conduct of the trial.
  • Unable or unwilling to communicate with staff, to provide written informed consent, or accept the randomized assignment.
  • Failure to complete run-in and baseline testing.
  • Lack support from health care provider or family members.
  • Other temporary intervening event, such as sick spouse, bereavement, or recent move.
  • Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise.
  • Current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder.
  • Any other condition, which, in the opinion of the investigators would impede competence or compliance or possibly hinder completion of the study.

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT01217216

Start Date

May 1 2009

End Date

October 1 2010

Last Update

September 15 2022

Active Locations (1)

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Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States, 70808