Status:
WITHDRAWN
Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic Myopia
Lead Sponsor:
L.V. Prasad Eye Institute
Collaborating Sponsors:
Pfizer
Conditions:
Myopic Choroidal Neovascular Membrane
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Intravitreal pegaptanib for treatment of choroidal neovascularisation secondary to pathologic myopia
Detailed Description
This is a Prospective Interventional, non-comparative study in 20 consecutive patients who will be selected from the outpatient services. After taking an informed consent, the patients will be given i...
Eligibility Criteria
Inclusion
- Should be willing to participate in the trial.
- Age less than 55 years.
- Best corrected visual acuity (BCVA) score of at least 5 letters (20/200), as assessed by ETDRS chart.
- Myopia of ≥ 6 Diopters.
- Fluorescein angiographic documentation of CNV.
Exclusion
- Ocular causes, or other ocular disorders leading to vision loss.
- Maculopathy not related to pathologic myopia.
- Pregnancy, lactation.
- Not willing to provide an informed consent.
- History of previous macular laser including PDT.
- Other forms of therapy including intravitreal injections.
- History of intraocular surgery in the past 3 months.
- Anticipated cataract surgery in the next 6 months.
- Any active infection or inflammation in the eye.
- Cases where good quality imaging is not possible, either due to hazy media or extremely high myopia.
- Patients with uncontrolled glaucoma, with IOP \> 21mm Hg on 2 or more medications.
- Patients with subfoveal scar or significant subretinal haemorrhage occupying more than 50% of lesion size.
- Eyes with previous retinal detachment.
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01218230
Start Date
December 1 2010
End Date
July 1 2012
Last Update
September 2 2015
Active Locations (1)
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1
LV Prasad Eye Institute
Hyderabad, Andhra Pradesh, India, 500034