Status:

COMPLETED

ALK21-003EXT: An Extension of Study ALK21-003 (NCT01218958) to Test the Long-term Safety of Medisorb® Naltrexone (VIVITROL®)

Lead Sponsor:

Alkermes, Inc.

Conditions:

Alcohol Dependence

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This was a Phase 3 multicenter extension of Alkermes' Study ALK21-003 (NCT01218958 \[the base study\]) that evaluated the safety of Medisorb® naltrexone (VIVITROL®) administered every 4 weeks for 48 w...

Detailed Description

All participants in this study received Medisorb naltrexone at double-blinded dose strengths (ie, 190 mg or 380 mg); no participant received placebo. Participants who had received Medisorb naltrexone ...

Eligibility Criteria

Inclusion

  • Primary
  • Completed study drug treatment in Study ALK21-003 (base study \[NCT01218958\])
  • Written informed consent for this extension study
  • Stable address and telephone; reconfirmation of contact's address and phone
  • Women with childbearing potential must agree to continue to use an approved method of birth control throughout study participation
  • Primary

Exclusion

  • Positive urine drug screen for opioids at Visit 1
  • Early termination of study drug in the base study
  • Pregnancy or lactation

Key Trial Info

Start Date :

August 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2004

Estimated Enrollment :

332 Patients enrolled

Trial Details

Trial ID

NCT01218971

Start Date

August 1 2002

End Date

September 1 2004

Last Update

December 24 2010

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