Status:

COMPLETED

Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies

Lead Sponsor:

Clinica Fabia Mater

Conditions:

Pregnancy

Iron Deficiency

Eligibility:

FEMALE

20-45 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether bovine lactoferrin is effective in preventing and curing iron deficiency and iron deficiency anemia in Hereditary Thrombophilia affected women during ...

Detailed Description

In industrialized and developing countries, iron deficiency (ID) and iron deficiency anemia (IDA) are highly prevalent in pregnant women. ID and IDA, in pregnant women as a consequence of an increased...

Eligibility Criteria

Inclusion

  • pregnant women with one of genetic thrombophilia markers as factor V Leiden, prothrombin 20210A mutation, antiphospholipid antibodies, hyperhomocysteinemia and deficiencies of antithrombin, protein C, or protein S.
  • pregnant women affected by HT and suffering of iron deficiency (ID) and iron deficiency anemia (IDA)
  • different trimester of pregnancy
  • previous miscarriage/s
  • previous preterm delivery/ies
  • iron disorders as iron deficiency and iron deficiency anemia are defined by the number of red blood cells \<4.000.000/mL, the hemoglobin concentration ≤ 11 g/dL, the total serum iron ≤ 30 mg/dL and serum ferritin ≤12 ng/mL.

Exclusion

  • absence of iron deficiency and iron deficiency anemia
  • non-pregnant women
  • uncomplicated pregnancies
  • no informed consent
  • other treatments of iron supplementation
  • recent blood transfusion
  • other concomitant diseases
  • ascertained allergy to milk proteins or to iron products.

Key Trial Info

Start Date :

February 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2011

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT01221844

Start Date

February 1 2010

End Date

May 1 2011

Last Update

June 27 2011

Active Locations (1)

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Clinica Fabia Mater

Rome, Rm, Italy

Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies | DecenTrialz