Status:
COMPLETED
Laryngeal Reflex Study Under Propofol Anesthesia: Effect of Intravenous Lidocaine
Lead Sponsor:
Thomas Erb
Conditions:
Laryngospasm
Eligibility:
All Genders
25-84 years
Phase:
PHASE3
Brief Summary
To describe respiratory and laryngeal responses to laryngeal stimulation during propofol anesthesia in children. To determine whether the co-administration of lidocaine blunts these reflex responses. ...
Detailed Description
Based on our previous work assessing the laryngeal reflex responses in children, the use of propofol appears to be promising regarding a low incidence of laryngospasm. Compared with a sevoflurane-base...
Eligibility Criteria
Inclusion
- 25 - 84 months
- gender: female / male
- elective surgery or diagnostic procedure requiring general anesthesia
Exclusion
- respiratory infection within the last 2 weeks
- reactive airway disease under therapy
- cardiovascular disease
- neuromuscular disease
- positive family history of malignant hyperthermia
- known hypersensitivity to the investigational medical product
- Participation in another study
- Inability of the parents to read and understand the participant's information
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT01222169
Start Date
September 1 2010
End Date
May 1 2012
Last Update
October 30 2015
Active Locations (1)
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1
University children's hospital beider Basel
Basel, Switzerland, 4031