Status:
COMPLETED
Evaluation of the Impact of Vitrification on Oocytes
Lead Sponsor:
Reproductive Medicine Associates of New Jersey
Conditions:
Fertilization
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the rate of cryosurvival of mature oocytes following vitrification, and to then compare the reproductive potential of vitrified oocytes relative to those whic...
Detailed Description
This study will recruit patients from the NY/NJ/CT/eastern PA area only. Cryopreservation of human oocytes has a great potential to preserve or extend fertility in the face of disease whose treatment...
Eligibility Criteria
Inclusion
- This study will recruit patients from the NY/NJ/CT/eastern PA area only.
- No prior failed IVF treatment cycle
- Female partner less than 35 years of age at time of onset of the IVF cycle
- Normal maximum prior day 3 follicle stimulating hormone (FSH) level (\< or = 10 IU/L)
- Total basal antral follicle count greater than or equal to 12
- Male partner with greater than 100,000 total motile spermatozoa Donor sperm is acceptable but the couples will be required to provide one additional vial for DNA analysis
- Body Mass Index (BMI) ≤ 32 kg/m2
Exclusion
- Diagnosis of chronic oligoovulation or anovulation (cycle typically occurring less often than every 38 days)
- Diagnosis of endometrial insufficiency
- Clinical indication for PGD (undergoing IVF with PGD to rule out a known genetic defect)
- Use of testicular aspiration or biopsy procedures to obtain sperm
- Unevaluated ovarian mass
- Presence of hydrosalpinges which communicate with the endometrial cavity
- Any contraindication to undergoing in vitro fertilization or gonadotropin stimulation
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2012
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT01223118
Start Date
August 1 2010
End Date
July 1 2012
Last Update
January 23 2013
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Reproductive Medicine Associates of New Jersey
Morristown, New Jersey, United States, 07960
2
Reproductive Medicine Assoicates of PA at Lehigh Valley
Allentown, Pennsylvania, United States, 18104