Status:

COMPLETED

Efficacy and Safety of Insulin Glargine Versus. Neutral Protamine Hagedorn (NPH) Insulin in Children With Type 1 Diabetes Above 6 Years Old.

Lead Sponsor:

Sanofi

Conditions:

Type 1 Diabetes Mellitus

Eligibility:

All Genders

6-17 years

Phase:

PHASE3

Brief Summary

Primary Objective: 6 To assess the efficacy of insulin glargine given once daily (QD) on glycosylated hemoglobin (HbA1c) levels over a period of 24 weeks in children with type 1 diabetes mellitus (T1...

Detailed Description

The study duration for each patient is 28 weeks +/- 7 day broken down as follows: * Screening phase: up to 2 weeks * Run-in phase: 1 week * Treatment phase: 24 weeks * Follow-up: 1 week

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • \- Paediatric patients diagnosed with T1DM aged at least 6 years to less than 18 years at screening.
  • Exclusion criteria:
  • Treatment with oral or parenteral glucose-lowering medications other than insulin.
  • HbA1c \< 7% or \> 12 % at screening.
  • The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Exclusion

    Key Trial Info

    Start Date :

    February 1 2011

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2014

    Estimated Enrollment :

    162 Patients enrolled

    Trial Details

    Trial ID

    NCT01223131

    Start Date

    February 1 2011

    End Date

    March 1 2014

    Last Update

    April 1 2014

    Active Locations (10)

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    Page 1 of 3 (10 locations)

    1

    Investigational Site Number 156006

    Beijing, China, 100020

    2

    Investigational Site Number 156001

    Beijing, China, 100045

    3

    Investigational Site Number 156007

    Beijing, China, 100730

    4

    Investigational Site Number 156009

    Changsha, China, 410011

    Efficacy and Safety of Insulin Glargine Versus. Neutral Protamine Hagedorn (NPH) Insulin in Children With Type 1 Diabetes Above 6 Years Old. | DecenTrialz