Status:
UNKNOWN
Study of Whether 15 mg Dose of Ketorolac IV is as Effective as a 30 mg Dose.
Lead Sponsor:
University of Calgary
Conditions:
Pain
Pain, Postoperative
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The primary aim of this study is to show the non-inferiority of 15 mg intraoperative dose of ketorolac as compared to the standard 30 mg ketorolac by looking at the VAS scores 4 hours after an adult s...
Detailed Description
Opioids have traditionally been the cornerstone of acute postoperative pain management. Problematic side effects such as nausea, vomiting, ileus, urinary retention, excess sedation, and respiratory de...
Eligibility Criteria
Inclusion
- Patients booked for 1-2 level spine laminectomies and/or decompression
- Adult 18 - 65 years
- Weight of 50 - 110 kg
Exclusion
- Previous lumbar laminectomy
- Current anticoagulant use with INR \> 1.2
- Narcotic use \> 4 weeks
- Known allergy or sensitivity to NSAID or morphine
- Renal insufficiency with creatinine \>100 umol/L
- Known liver disease
- History of gastrointestinal bleeding
- Pregnancy, history of bronchial asthma
- NSAID use 2 days before surgery.
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2011
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01230463
Start Date
September 1 2010
End Date
September 1 2011
Last Update
October 29 2010
Active Locations (1)
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1
Foothills Medical Centre
Calgary, Alberta, Canada, T2N 2T9