Status:

COMPLETED

Biomarkers in Tissue Samples From Patients With Acute Promyelocytic Leukemia

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

Up to 120 years

Brief Summary

RATIONALE: Studying samples fo tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research study is studying...

Detailed Description

OBJECTIVES: * Demonstrate that S100A10 is expressed on APL cells and that levels of S100A10 correspond to the amount of fibrinolytic activity. * Evaluate the impact of ATRA on S100A10 level and fibri...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of acute promyelocytic leukemia
  • Available cryopreserved cells from diagnosis or cryopreserved cells from remission (germline)
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    November 1 2010

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 1 2011

    Estimated Enrollment :

    10 Patients enrolled

    Trial Details

    Trial ID

    NCT01232855

    Start Date

    November 1 2010

    End Date

    February 1 2011

    Last Update

    October 2 2015

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