Status:
SUSPENDED
Mesenchymal Stem Cells Treat Liver Cirrhosis
Lead Sponsor:
Yufang Shi
Collaborating Sponsors:
Soochow University
Conditions:
Liver Cirrhosis
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to investigate the efficacy of umbilical cord mesenchymal stem cells (MSCs) transfusion in the treatment of liver cirrhosis. Liver function will be monitored by serum anal...
Detailed Description
Patients with liver cirrhosis will be randomly divided into three groups. Umbilical cord MSCs will be infused to patients using interventional method via hepatic artery for one group. The catheter wil...
Eligibility Criteria
Inclusion
- Age 18-70 years.
- Imaging evidences of liver cirrhosis.
- Child-Plough score of 8 or more.
- Model for End-Stage Liver Disease score of 20 or more.
Exclusion
- Liver tumor on ultrasonography, CT or MRI examination.
- Problems in organs other than liver (e.g. heart or lungs).
- History of moderate to severe hepatic encephalopathy or variceal bleeding.
- Imaging evidences of vascular thromboses.
- Coma.
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2019
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01233102
Start Date
October 1 2009
End Date
December 1 2019
Last Update
February 22 2016
Active Locations (1)
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1
First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China, 215006