Status:
COMPLETED
Cord Blood Serum in the Treatment of Ocular Surface Diseases
Lead Sponsor:
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions:
Graft vs Host Disease
Sjogren's Disease
Eligibility:
All Genders
18+ years
Brief Summary
Human autologous serum (AS) eye drops have been successfully used in the treatment of severe ocular surface disorders and the enhancement of corneal wound healing, due to their growth factor (GF) cont...
Detailed Description
The regular collection and banking of cord blood remaining in the placenta after baby's delivery started in the early 1990s and was prompted by the observation that cord blood shows an immunological i...
Eligibility Criteria
Inclusion
- to suffer from GVHD after bone marrow transplantation or SS-I
- presence of permanent or transient corneal epithelial defects scored \> 2 , according to DEWS severity classification
- to be in a general healthy condition
- signature of study consent for participation and personal data treatment.
Exclusion
- to suffer from glaucoma and being under treatment with antiglaucomatous drugs
- to have received refractive surgery over the past year
Key Trial Info
Start Date :
February 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01234623
Start Date
February 1 2010
End Date
May 1 2011
Last Update
May 26 2011
Active Locations (1)
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1
Ophthalmology Unit, Dept.of Specialistic Surgery and Anesthesiological Sciences
Bologna, Bologna, Italy, 40138