Status:

TERMINATED

A Study To Examine The Efficacy And Safety Of Pramlintide+Metreleptin In Obese Subjects

Lead Sponsor:

AstraZeneca

Collaborating Sponsors:

Takeda Pharmaceuticals North America, Inc.

Conditions:

Obesity

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

Following screening, eligible subjects will be enrolled into a 6-week Low Calorie Diet (LCD) lead-in period. Subjects who lose at least 2% of their body weight at the end of the 6-week LCD lead-in per...

Eligibility Criteria

Inclusion

  • Is obese with a BMI ≥35 to ≤45 kg/m2.
  • Has stable body weight (not varying by \>5% within 3 months prior to study start).
  • Meets certain requirements with respect to concomitant medications.
  • Has not smoked or used nicotine-containing products for at least 12 months prior to study start.

Exclusion

  • Has not been enrolled in a weight loss program within 2 months prior to study start.

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

213 Patients enrolled

Trial Details

Trial ID

NCT01235741

Start Date

January 1 2011

End Date

September 1 2011

Last Update

April 15 2015

Active Locations (18)

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Page 1 of 5 (18 locations)

1

Research Site

Greenbrae, California, United States

2

Research Site

La Jolla, California, United States

3

Research Site

Denver, Colorado, United States

4

Research Site

Winter Park, Florida, United States