Status:
UNKNOWN
The Risk of Myocardial Infarction in Users of Antipsychotic Agents
Lead Sponsor:
London School of Hygiene and Tropical Medicine
Collaborating Sponsors:
University College, London
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18+ years
Brief Summary
A number of studies have suggested an association between the use of antipsychotic agents and cardiovascular mortality. However, the relationship between cardiac events and the use of antipsychotic dr...
Detailed Description
This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central them...
Eligibility Criteria
Inclusion
- Patients in GPRD practices that agreed to linkage with the MINAP database
- Age over 18
- Self-controlled case-series: patients who received an antipsychotic agent during up to standard (UTS) follow-up in the GPRD
- Self-controlled case-series: patients who experienced a first record of MI at least 12 months after the start of UTS follow-up period in the GPRD data record
Exclusion
- Patients will be excluded after experiencing their first MI
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2014
Estimated Enrollment :
90000 Patients enrolled
Trial Details
Trial ID
NCT01236274
Start Date
November 1 2010
End Date
December 1 2014
Last Update
November 8 2010
Active Locations (1)
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1
London School of Hygiene and Tropical Medicine
London, United Kingdom, WC1E 7HT