Status:
COMPLETED
A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers
Lead Sponsor:
University of Southern Denmark
Conditions:
Metformin
Organic Cation Transporter 2
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that renal clearance...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Written consent
- rs316019 genotyped
- Age 18-65 years old
Exclusion
- Daily medication
- Alcohol abuse
- Pregnancy
- Breastfeeding
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01237522
Start Date
August 1 2010
End Date
December 1 2010
Last Update
December 29 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Institute of Public Health, Clinical Pharmacology, University of Southern Denmark
Odense, Denmark, 5000