Status:
COMPLETED
Intra-articular Hyaluronic Acid in Mild to Moderate Knee Osteoarthritis
Lead Sponsor:
Technical University of Munich
Conditions:
Osteoarthritis
Eligibility:
All Genders
18-95 years
Brief Summary
Objective: To assess the impact of intraarticular hyaluronic acid (HA) on clinical outcome and on volumetric and T2 relaxation based changes of articular cartilage in mild to moderate osteoarthritis ...
Detailed Description
Introduction: The medical management of knee osteoarthritis (OA performing intra-articular treatment with hyaluronic acid (HA) has recently become more widely accepted. The effectiveness of HA regard...
Eligibility Criteria
Inclusion
- History of mild to moderate OA
- OA grade II
Exclusion
- Intraarticular injections in the affected knee
- Oral application of glucosamine and chondroitin sulphate during the last 6 months prior to the beginning of the study
- Clinically significant knee joint effusion
- Neoplasm
- Diabetes mellitus
- Osteonecrosis
- Rheumatoid arthritis or any other inflammatory arthritis diagnosed by American College of Rheumatology criteria.
Key Trial Info
Start Date :
June 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT01239810
Start Date
June 1 2005
End Date
December 1 2008
Last Update
December 9 2010
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