Status:

UNKNOWN

MACS Study - Microparticles and Coagulation in Sickle Cell Disease

Lead Sponsor:

University College, London

Collaborating Sponsors:

Guy's and St Thomas' NHS Foundation Trust

The Whittington Hospital NHS Trust

Conditions:

Sickle Cell Disease

Eligibility:

All Genders

Brief Summary

Sickle cell disease (SCD) is an inherited disorder of the red blood cell. It is now the commonest genetic disorder in the UK and of childhood stroke, with up to 40% of children having a stroke (clinic...

Detailed Description

Purpose and design * Why is it needed? The purpose of this study is to try and identify a measurable parameter to act as a disease indicator in sickle cell disease. The reason such a parameter is nee...

Eligibility Criteria

Inclusion

  • Subject
  • Patient (or parent if child) able to give informed consent Compound heterozygote or homozygote for a sickling disorder (i.e. has sickle cell disease) Having a blood test in any case
  • Healthy volunteer
  • Person (or parent if child) able to give informed consent If a child, having a blood test or cannula inserted in any case Ethnically matched - of African origin Must know their sickle cell status or have it tested as part of the study and agree to have this result given to them and their G.P.

Exclusion

  • Subject

Key Trial Info

Start Date :

December 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT01242878

Start Date

December 1 2010

Last Update

November 18 2010

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Whittington Hospital NHS Trust

London, United Kingdom, N19 5NF

2

University College London Hospitals NHS Foundation Trust

London, United Kingdom, NW1 2PJ

3

Guy's and St Thomas' NHS Foundation Trust

London, United Kingdom, SE1 7EH