Status:

COMPLETED

OZURDEX in Age Related Macular Degeneration as Adjunct to Ranibizumab

Lead Sponsor:

McMaster University

Collaborating Sponsors:

Hamilton Health Sciences Corporation

St. Joseph's Healthcare Hamilton

Conditions:

Wet Macular Degeneration

Eligibility:

All Genders

18-100 years

Phase:

PHASE2

Brief Summary

In the Western World, Age Related Macular Degeneration (ARMD) is a leading cause of blindness. This disease was once thought to be a natural part of aging, but recent research has introduced effective...

Detailed Description

Age Related Macular Degeneration (ARMD or AMD) is the leading cause of blindness in North America. There are two types of ARMD: dry and wet. Both forms of ARMD cause a progressive loss of central visi...

Eligibility Criteria

Inclusion

  • Patients with wet age-related macular degeneration (ARMD) with evidence of sub-foveal choroidal neo-vascularization (CNV)
  • Patients greater than the age 18 years old (male or female)
  • Visual acuity must be between 20/40 and 20/320 in the study eye.

Exclusion

  • Patients with CNV from causes other than ARMD
  • Patients having intra-ocular surgery within past 3 months on study eye
  • Patients with medically uncontrolled glaucoma
  • Patients with prior vitreous/retinal surgery
  • Patients with a history of past CNV treatment in study eye
  • Patients with other ocular conditions causing vision loss that could confound the analysis of ARMD
  • Individuals with a disability preventing accurate vision testing

Key Trial Info

Start Date :

March 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2015

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01243086

Start Date

March 1 2011

End Date

May 1 2015

Last Update

April 6 2018

Active Locations (1)

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St. Joseph's Healthcare Hamilton Regional Eye Centre

Hamilton, Ontario, Canada, L8G 5E4