Status:
COMPLETED
In Vivo Assessment of Silver Biomaterial Nano-Toxicity
Lead Sponsor:
University of Utah
Conditions:
Healthy
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
PHASE2
Brief Summary
Nanotechnology is the controlled generation and manipulation of matter in dimensions less than 100 nm. Silver has been used for its bactericidal properties. The investigators propose to study the Amer...
Eligibility Criteria
Inclusion
- Subjects must be \> 18-80 years old will be included.
Exclusion
- Females of child-bearing potential, defined as women physically capable of becoming pregnant, including women whose career, lifestyle, or sexual orientation precludes intercourse with a male partner and women whose partners have been sterilized by vasectomy or other means will be excluded unless they are using 2 barrier birth control methods (i.e., diaphragm, condom, intrauterine device, sponge or spermicide) or hormonal contraceptive method.
- Any female subject who is nursing will be excluded. Subject with has a history of heavy metal allergy (including silver) or a history of asthma or COPD or renal impairment defined by a creatinine clearance below 30 ml/min.
- Subjects with symptoms of an active upper respiratory infection at time of consent will also be excluded.
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2011
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT01243320
Start Date
December 1 2010
End Date
July 1 2011
Last Update
August 25 2015
Active Locations (1)
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1
University of Utah Hospital and Clinics
Salt Lake City, Utah, United States, 84132