Status:

COMPLETED

The Effects of Two Functional Electrical Stimulation Cycling Paradigms

Lead Sponsor:

Thomas Jefferson University

Collaborating Sponsors:

The Craig H. Neilsen Foundation

Magee Rehabilitation Hospital

Conditions:

Spinal Cord Injury

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

PHASE3

Brief Summary

Background: People with spinal cord injury (SCI) are at risk for many health conditions, some of which can be decreased with exercise. Cycling with Functional Electrical Stimulation (FES) is one way ...

Eligibility Criteria

Inclusion

  • Cervical or thoracic SCI of greater than 6 months duration
  • American Spinal Injury Association Impairment Scale (AIS) levels A (motor and sensory complete) or B (motor complete)
  • Intact lower motor neurons to the quadriceps, hamstrings, and gluteal muscles

Exclusion

  • History of renal or bladder stones or renal impairment
  • Presence of conditions that require chronic steroids
  • Symptomatic or known cardiac disease
  • Pulmonary disease limiting exercise tolerance
  • Ventilator dependency
  • Implanted devices that may be adversely affected by the FES system
  • Lower extremity fragility fractures in the previous 3 months
  • Severe spasticity in legs
  • Presence of a Grade 2 or higher pressure ulcer
  • Severely limited range of joint motion
  • Heterotopic ossification of joints in the lower extremities
  • Uncontrolled autonomic dysreflexia
  • Dislocation of one or both hips
  • Pregnancy or plans to become pregnant during the study
  • Post menopausal, if female
  • Current seizure disorder
  • Participation in activities involving electrical stimulation or activity based therapy within the past 3 months
  • Participation in a neuroregenerative intervention within the past 12 months

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2013

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT01244594

Start Date

July 1 2010

End Date

October 1 2013

Last Update

January 8 2014

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Magee Rehabilitation Hospital

Philadelphia, Pennsylvania, United States, 19102

2

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States, 19107

3

Thomas Jefferson University

Philadelphia, Pennsylvania, United States, 19107