Status:
ENROLLING_BY_INVITATION
Characterization of Human Memory Immune Responses to Prior Yellow Fever Vaccination
Lead Sponsor:
Emory University
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Yellow Fever Vaccine
Eligibility:
All Genders
18+ years
Brief Summary
The objective of this study is to study immune memory generated against the yellow fever (YFV) vaccine in participants who have previously received the vaccine. Volunteers will not receive vaccine sho...
Detailed Description
The goal of this study is to characterize immune memory in humans who have previously received yellow fever vaccine. The project is designed to study the magnitude and persistence of both humoral, and...
Eligibility Criteria
Inclusion
- Able to understand and give informed consent
- Age 18-45 years (Group 1) or 55 years and above (Group 2) at the time of yellow fever vaccination
- Documentation (international certificate of vaccination (yellow card) or medical record) indicating receipt of yellow fever vaccine.
Exclusion
- Recipient of any vaccines within 30 days before the study visit (not applicable to older adults)
- History of a progressive and severe chronic medical condition resulting in impaired immunity (such as diabetes, kidney or liver dysfunction)
- Required use of immunosuppressive medications
- Reporting HIV, Hepatitis B (surface antigen positive) or Hepatitis C infections (antibody positive) on the medical/health history form
- Recipient of a blood product or immune globulin product within 42 days of study visit
- Reporting pregnancy
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2029
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01244802
Start Date
November 1 2010
End Date
October 1 2029
Last Update
November 4 2024
Active Locations (1)
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1
The Hope clinic of Emory Vaccine Center
Decatur, Georgia, United States, 30030