Status:

WITHDRAWN

The Effect of Artificial Sweeteners on Blood Glucose Response

Lead Sponsor:

Northumbria University

Conditions:

Taste Receptors

Nutrient Sensing

Eligibility:

All Genders

18-45 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether the presece of the artificial sweeteners aspartame, saccharin and asceulfame-k affect the blood glucose responses to an orally incested glucose soluti...

Detailed Description

Sweet taste receptors, similar to those located on the lingual taste buds have been located along in the lining of the gut. Recent studies have demonstrated that activation of these sweetness taste re...

Eligibility Criteria

Inclusion

  • Healthy subjects
  • Aged 18-45 years
  • BMI (19-25 kg/m2)
  • Weight stable in past 3 months

Exclusion

  • Smoking
  • Females who are pregnant of breastfeeding
  • Regular intake of emdication, other than females taking oral contraceptives
  • Medical illness
  • Gastrointestinal disorders
  • Food allergies

Key Trial Info

Start Date :

November 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2011

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01246492

Start Date

November 1 2010

End Date

May 1 2011

Last Update

May 18 2012

Active Locations (1)

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1

Brain, Performance and Nutrition Research Centre- Northumbria University

Newcastle upon Tyne, United Kingdom, NE1 8ST