Status:
COMPLETED
Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
Up to 21 years
Brief Summary
RATIONALE: Studying bone marrow samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: Thi...
Detailed Description
OBJECTIVES: * To compare the frequency of germline telomerase mutations in pediatric patients with acute myeloid leukemia (AML) demonstrating prolonged myelosuppression, defined as ≥ 1 episode \> 35 ...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of acute myeloid leukemia
- Enrolled on CCG-2961 and meeting 1 of the following criteria:
- More than 35 days to recover to an ANC \> 500/mm³ after any course of chemotherapy
- Consistently recovered \< 35 days to an ANC \> 500/mm³ after all courses of chemotherapy
- Available cryopreserved cell from diagnostic and end-of-therapy samples
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
234 Patients enrolled
Trial Details
Trial ID
NCT01247584
Start Date
November 1 2010
Last Update
May 19 2016
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