Status:

UNKNOWN

Impact of Raltegravir on the Viral Reservoirs

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

HIV Infection

Eligibility:

All Genders

18-60 years

Brief Summary

The objective of the antiretroviral treatment is to inhibit the viral replication, estimated(appreciated) by the measure of the viral plasmatic load(responsibility). In this inhibition of the viral re...

Detailed Description

20 patients will be included and followed over a period of 12 months Population of the essay Criteria of inclusion: Patients from 18 years to 60 years HIV + treated(handled): * Patients presenting...

Eligibility Criteria

Inclusion

  • Patients from 18 years to 60 years HIV + treated(handled):
  • Patients presenting an undetectable viral load(responsibility) for at least 6 months and no more than year, by the use of a tritherapy containing 2 NUC + 1 IP.
  • Patients presenting an immunosuppression "average" with a rate of T CD4 understood between 350 and 500 cells(units) by ml.
  • Patients known for a perfect observance.

Exclusion

  • Preliminary Use of an inhibitor of the integrase
  • Patients presenting an opportunist infection and\\or an evolutionary cancer
  • Patients benefiting from a treatment by IL-2, interferon-alpha, steroids or the other medicines known to modify the immunity.
  • Pregnant Women

Key Trial Info

Start Date :

January 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2011

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT01249560

Start Date

January 1 2011

End Date

March 1 2011

Last Update

November 30 2010

Active Locations (1)

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1

Dellamonica

Nice, Alpes Maritimes, France, 06200