Status:

COMPLETED

Medico-economic Evaluation of a Non-chirurgical Pulmonary Valve Replacement (REVALV)

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

Ministry of Health, France

Conditions:

Dysfunction of the Prosthetic Conduct

Lesions of the Right Ventricular Outflow Tract

Eligibility:

All Genders

5-70 years

Phase:

NA

Brief Summary

This prospective interventional study is designed to evaluate the cost/advantage ratio in the treatment of lesions of the right ventricular outflow tract using transcatheter pulmonary valved stent (Me...

Detailed Description

Rational : transcatheter valve insertion is a new technique enlarging the armamentarium of the treatment of RVOT obstruction and insufficiency. It real place as compared to bare stent implantation and...

Eligibility Criteria

Inclusion

  • for the study:
  • Lesions of the right ventricular outflow tract in need of surgery for stenosis or regurgitation
  • for the Melody arm:
  • A 5 to 70 years old patient
  • Weight \>= 30kg
  • RVOT \<= to 22mm
  • Patient with a dysfunction circumferential prosthetic conduct of diameter \>= to 16mm.

Exclusion

  • Vein anatomy incompatibility with a 22Fr delivery health
  • Left heart implantation
  • RVOT incompatible with a anchoring of the stent (lik in patient operated of a tetralogy of fallot)
  • Coronary anomaly with a coronary artery naer the RVOT
  • Sever obstruction of the RVOT incompatible with balloon expansion
  • Central vein obstruction
  • Ongoing infection
  • Active endocarditis
  • Allergy for heparin or aspirin
  • Pregnancy

Key Trial Info

Start Date :

March 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

93 Patients enrolled

Trial Details

Trial ID

NCT01250327

Start Date

March 1 2009

End Date

August 1 2013

Last Update

October 18 2017

Active Locations (1)

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1

Hôpital Necker Enfants Malades

Paris, France, 75015