Status:
COMPLETED
Biomarkers in Bone Marrow Samples From Patients With Acute Myeloid Leukemia
Lead Sponsor:
ECOG-ACRIN Cancer Research Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
16-60 years
Brief Summary
RATIONALE: Studying samples of bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: ...
Detailed Description
OBJECTIVES: * To rigorously examine fractionated hematopoietic stem and progenitor cells from patients with acute myeloid leukemia (AML). * To define somatic mutations occurring in de novo AML, inclu...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of acute myeloid leukemia
- Bone marrow samples must meet 1 of the following criteria:
- Normal karyotype from patients enrolled on ECOG-1900 archived at the ECOG Leukemia Tissue Bank
- Live, sortable mononuclear cells prepared at the time of initial diagnosis (slow-frozen in media with 10% DMSO OR fresh cells shipped immediately
- Age-matched healthy control samples from commercial providers
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
May 15 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 15 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01251159
Start Date
May 15 2009
End Date
June 15 2009
Last Update
May 17 2017
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